On November 25, 2009, Replikins issued its latest biochemical analysis of the H1N1 virus. The new data shows a reduction in Replikin count just as the supply of biological vaccines is ramping up. A similar decrease signaled the end of each of the three influenza pandemics of the last century (H1N1, H2N2, and H3N2), the end of the SARS outbreak in 2003, and the end of the H5N1 (Avian Flu) outbreak in humans in 2008.
The company posits that the current H1N1 pandemic demonstrates the inherent limitations of biological vaccines, which simply do not permit the timely delivery of vaccine in sufficient quantities before an emergent viral disease like H1N1 has come and gone.
The best intentions and efforts of governments, pharmaceutical firms, and public health authorities cannot overcome the absence of advance warning, and the many months required from outbreak to delivery of the vaccine.
Replikins has tested a technology for the faster development and deployment of safe and effective influenza vaccines. The company has now produced completely synthetic vaccines based on both new and conserved Replikin structures, which exclude all biological components and any contact with them. The process eliminates unwanted side effects from contaminants and the need for preservatives such as thimerosol. Synthetic Replikin vaccines made in seven days, given orally or intranasally, recently have been found independently to be effective in blocking emergent viruses including H5N1 in chickens, where it totally blocked virus excretion and thus potentially, virus reservoir formation.